PXD061304 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Parenchymal and Dyshorric Fibrillar Amyloid Pathology in the rTg-D Rat Model of Cerebral Amyloid Angiopathy Type-2 |
| Description | Whole brain tissue proteomics from rat models of cerebral small vessel disease and Alzheimer's disease, including the rTg-DI model of Cerebral Amyloid Angiopathy (CAA) Type-1, the rTg-D model of CAA Type-2 with both hemizygous and homozygous animals, and the TgSD-AD model of Alzheimer's Disease. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-11-18 |
| AnnouncementXML | Submission_2025-11-17_18:08:32.758.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Dennis Province |
| SpeciesList | scientific name: Rattus norvegicus (Rat); NCBI TaxID: NEWT:10116; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | timsTOF Pro 2 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-02-28 06:11:18 | ID requested | |
| ⏵ 1 | 2025-11-17 18:08:33 | announced | |
Publication List
| 10.1016/j.ajpath.2025.06.008; |
| Schrader JM, Xu F, Zhu X, Majchrzak M, Davis J, Van Nostrand WE, Parenchymal and Dyshoric Fibrillar Amyloid Pathology in the rTg-D Rat Model of Cerebral Amyloid Angiopathy Type-2. Am J Pathol, 195(11):2213-32(2025) [pubmed] |
Keyword List
| submitter keyword: Cerebral amyloid angiopathy, preclinical model, Alzheimer's disease, cerebral small vessel disease |
Contact List
| William E. Van Nostrand |
|---|
| contact affiliation | University of Rhode Island |
| contact email | wvannostrand@uri.edu |
| lab head | |
| Dennis Province |
|---|
| contact affiliation | UAMS |
| contact email | dprovince@uams.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/11/PXD061304 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD061304
- Label: PRIDE project
- Name: Parenchymal and Dyshorric Fibrillar Amyloid Pathology in the rTg-D Rat Model of Cerebral Amyloid Angiopathy Type-2
