PXD061300-1

PXD061300 is an original dataset announced via ProteomeXchange.

Title	Retinal proteomic analysis in rd10 mouse model of retinitis pigmentosa following heterozygous TAK1 deficiency using LC-MS/MS
Description	To decipher the protective mechanisms underlying microglia specific heterozygous TAK1 deficiency in rd10 mouse model of retinitis pigmentosa, we analyzed the retinal proteomic profiles of normal C57BL/6J mice, tamoxifen-treated Cx3cr1CreER/+;Tak1fl/+, vehicle-treated rd10;Cx3cr1CreER/+;Tak1fl/+, and tamoxifen-treated rd10;Cx3cr1CreER/+;Tak1fl/+ mice using a data-independent acquisition-based mass spectrometry (DIA).
HostingRepository	PRIDE
AnnounceDate	2025-04-17
AnnouncementXML	Submission_2025-04-16_22:34:22.428.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jing Zhang
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	carbamoylated residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2025-02-28 02:56:37	ID requested
⏵ 1	2025-04-16 22:34:22	announced

Dataset with its publication pending

submitter keyword: Retina,Mouse, TAK1, retinitis pigmentosa, LC-MS/MS

Bin Lin
contact affiliation	The Hong Kong Polytechnic University
contact email	b.lin@polyu.edu.hk
lab head
Jing Zhang
contact affiliation	The Hong Kong Polytechnic University
contact email	jing0114.zhang@connect.polyu.hk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/04/PXD061300

PRIDE project URI

• PRIDE
  1. PXD061300
     1. Label: PRIDE project
     2. Name: Retinal proteomic analysis in rd10 mouse model of retinitis pigmentosa following heterozygous TAK1 deficiency using LC-MS/MS