PXD061144 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | In-depth plasma proteomics of patients with suspected lung cancer (lung adenocarcinoma and non-cancer controls) with HiRIEF LC-MS/MS |
| Description | Here, we present an in-depth proteomic profiling of pre-diagnostic plasma samples from 114 individuals with suspected lung cancer, including 57 patients diagnosed with stage III-IV lung adenocarcinoma (LUAD) and 57 non-cancer controls. Plasma samples were depleted of high-abundant proteins, and proteomic analysis was performed using high-resolution isoelectric focusing (HiRIEF) coupled with liquid chromatography tandem mass spectrometry (LC-MS/MS), with relative quantification by isobaric tandem mass tags (TMT16-plex). |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-11-11 |
| AnnouncementXML | Submission_2025-11-11_12:30:59.211.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Noora Sissala |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-02-24 11:21:52 | ID requested | |
| ⏵ 1 | 2025-11-11 12:31:00 | announced | |
Publication List
| 10.1038/s42004-025-01753-2; |
| Sissala N, Baba, č, i, ć H, Leo IR, Cao X, Forshed J, Eriksson LE, Lehti, ö J, Fredolini C, Å, berg M, Pernemalm M, Comparative evaluation of Olink Explore 3072 and mass spectrometry with peptide fractionation for plasma proteomics. Commun Chem, 8(1):327(2025) [pubmed] |
Keyword List
Contact List
| Janne Lehtiö |
|---|
| contact affiliation | Department of Oncology-Pathology, Karolinska Institutet |
| contact email | janne.lehtio@ki.se |
| lab head | |
| Noora Sissala |
|---|
| contact affiliation | Karolinska Institutet |
| contact email | noora.sissala@ki.se |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/11/PXD061144 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD061144
- Label: PRIDE project
- Name: In-depth plasma proteomics of patients with suspected lung cancer (lung adenocarcinoma and non-cancer controls) with HiRIEF LC-MS/MS
