PXD061129-1

PXD061129 is an original dataset announced via ProteomeXchange.

Title	Bulk proteomics of naive human dorsal root ganglion
Description	Study Purpose: This study set out to a) provide a quantitative proteomic reference for the human DRG and nerve root and b) explore sexual dimorphism in these tissues. Data Collection: DIA-PASEF proteomics was performed on hDRG tissue from donors. Primary Conclusion: Multi-omic integration with human DRG proteomics highlights TNFa signaling as a relevant sexually dimorphic pathway in the periphery.
HostingRepository	PRIDE
AnnounceDate	2025-09-22
AnnouncementXML	Submission_2025-09-22_06:08:19.470.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Allison Barry
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	timsTOF HT

Revision	Datetime	Status	ChangeLog Entry
0	2025-02-24 04:39:13	ID requested
⏵ 1	2025-09-22 06:08:20	announced

10.1101/2024.12.06.626968;

Barry AM, Sondermann JR, Lesnak JB, Xian F, Franco-Enz, á, stiga Ú, O'Brien JA, Gomez-Varela D, Schackmuth MK, Shiers S, Price TJ, Schmidt M, signalling as a relevant sexually dimorphic pathway. Pain, 166(10):2386-2402(2025) [pubmed]

10.1097/j.pain.0000000000003656;

Barry AM, Sondermann JR, Lesnak JB, Xian F, Franco-Enz, á, stiga Ú, O'Brien JA, Gomez-Varela D, Schackmuth MK, Shiers S, Price TJ, Schmidt M, signalling as a relevant sexually dimorphic pathway. bioRxiv, ():(2025) [pubmed]

submitter keyword: dia-pasef, proteomics,dorsal root ganglia, drg, dia, sensory neurons

Manuela Schmidt
contact affiliation	University of Vienna
contact email	manuela.schmidt@univie.ac.at
lab head
Allison Barry
contact affiliation	University of Vienna
contact email	allison.barry@univie.ac.at
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD061129

PRIDE project URI

• PRIDE
  1. PXD061129
     1. Label: PRIDE project
     2. Name: Bulk proteomics of naive human dorsal root ganglion