PXD061095-1

PXD061095 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	CUL4A-DDB1-DCAF10 is an n-recognin for Nt-acetylated Src kinases
Description	cotranslational n-terminal modifications such as methionine excision, acetylation, and myristoylation contribute to protein stability, localization and three-dimensional folding. Disruption of these modifcations expose short n-terminal degron motifs that ultimately trigger protein degradation through the ubiqutin-proteasome system, safeguarding the proteome.
HostingRepository	PRIDE
AnnounceDate	2025-12-05
AnnouncementXML	Submission_2025-12-04_19:57:40.421.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tanja Bange
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF; Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-02-23 08:13:19	ID requested
⏵ 1	2025-12-04 19:57:41	announced

Publication List

10.21203/RS.3.RS-6184818/V1;

10.21203/RS.3.RS-6184818/V1;

Keyword List

submitter keyword: n-t acetylation, SFKs, N-degron DCAF10, ubiquitination, Nt- myristoylation,Cotranslational modifications, n-recognin

submitter keyword: n-t acetylation, SFKs, N-degron DCAF10, ubiquitination, Nt- myristoylation,Cotranslational modifications, n-recognin

Contact List

Tanja Bange
contact affiliation	institute of Medical psychology, LMU munich
contact email	tanja.bange@med.uni-muenchen.de
lab head
Tanja Bange
contact affiliation	LMU Munich
contact email	tanja.bange@med.uni-muenchen.de
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD061095
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD061095

PRIDE project URI

Repository Record List

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