PXD061034-1

PXD061034 is an original dataset announced via ProteomeXchange.

Title	H2O2, O2, and C-H Activation by Artificial Copper Proteins (ArCuPs)
Description	De novo-designed artificial Cu protein (ArCuP), 3SCC, featuring a trigonal Cu(His)3 binding environment, has been shown to activate H2O2, O2, and benzylic C-H bonds of abiotic substrates. We outline the mechanism of ArCuP-catalyzed C-H peroxidation of one such abiotic substrate, the peroxidation of benzyl alcohol to benzaldehyde.
HostingRepository	PRIDE
AnnounceDate	2026-06-01
AnnouncementXML	Submission_2026-05-31_16:21:40.863.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sandeep Misra
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	monohydroxylated residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2025-02-20 20:37:54	ID requested
⏵ 1	2026-05-31 16:21:41	announced

10.1002/chem.202501245;

Prakash D, Wu Y, Misra SK, Sampath N, Wang B, Chakraborty S, . Chemistry, 31(52):e01245(2025) [pubmed]

submitter keyword: Cu proteins,De novo protein design

Sandeep Misra
contact affiliation	University of Mississippi
contact email	skmisra@olemiss.edu
lab head
Sandeep Misra
contact affiliation	University of Mississippi
contact email	skmisra@olemiss.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD061034

PRIDE project URI

• PRIDE
  1. PXD061034
     1. Label: PRIDE project
     2. Name: H2O2, O2, and C-H Activation by Artificial Copper Proteins (ArCuPs)