PXD060928-1
PXD060928 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | HX study on SMARCA2/A4(BRM/BRG1) degraders acting via the recruitment of FBXO22 |
| Description | Filetypes: DATE_PeptideReference_MSMS.csv - contains the identity of peptides and expected retention times to be tracked over the experiment. These are determined from an MSMS experiment, see *MSMS* in the filename. Use file dates for file associations. Files are included for experiments involving APO FBXO22 +/- BRM or BRM+Ligand. All data uses the FBXO22.fasta sequence file. Raw Mass Spectrum Files: There are three types, all have been converted to MZXML from Thermo .RAW format. -One MSMS file (producing the identifications to be tracked through the experiment) -Pool files - ms-only files of unlabeled peptides run on the day of the experiment. -Timeseries Files - ms-only files containing deuterated timepoints. *Note, there may be two sets of apo files as experiments may be collected at different dates and a new apo dataset is often collected. Search Engine Files: ExMS 2 software used to produce "finaltables" result files: PMID: 31082210, DOI: 10.1021/acs.analchem.9b01682 A unique identifier is included in each type of result file, provided below. *MSMS* - file contains the identity of peptides and expected retention times to be tracked over the experiment. These are determined from an MSMS experiment, see *MSMS* in the filename. Use file dates for file associations. *Pool* - Output from ExMS2 on reference ms-only unlabeled data *sec* - Timepoint from the experiment. Other information is provided in the filename of each result file, note that the name of the raw mass spectrum file used to produce the result file is included in the result file name. |
| HostingRepository | MassIVE |
| AnnounceDate | 2025-09-08 |
| AnnouncementXML | Submission_2025-09-08_09:59:49.676.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Benjamin Walters |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-02-18 11:30:35 | ID requested | |
| ⏵ 1 | 2025-09-08 09:59:50 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: SMARCA2/A4, FBXO22, Hydrogen/deuterium exchange, DatasetType:Other (Hydrogen/deuterium exchange) |
Contact List
| Benjamin Walters | |
|---|---|
| contact affiliation | Genentech |
| contact email | walters.benjamin@gene.com |
| lab head | |
| Benjamin Walters | |
| contact affiliation | Genentech |
| contact email | walters.benjamin@gene.com |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v09/MSV000097140/ |
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