PXD060840 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The mass spectrometry analysis detected differences in protein lactylation in B16 cells after lactic acid treatment. |
| Description | In this experiment, we treated the B16 cell line with lactic acid and performed peptide immunoprecipitation using anti-lactylation antibodies. We then detected the overall lactylation modifications of intracellular proteins after lactic acid treatment using mass spectrometry. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-07-21 |
| AnnouncementXML | Submission_2025-07-20_16:07:09.668.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | pu wang |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
| ModificationList | acetylated residue |
| Instrument | LTQ Orbitrap |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-02-14 21:58:59 | ID requested | |
| ⏵ 1 | 2025-07-20 16:07:10 | announced | |
Publication List
| 10.1038/s41598-025-04225-8; |
| Du B, Xiao M, Gao L, Lactic acid inhibits melanin synthesis by regulating histone H3 lactylation and suppressing tyrp1 transcription in B16 melanoma cells. Sci Rep, 15(1):25816(2025) [pubmed] |
Keyword List
| ProteomeXchange project tag: Antibodies (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project |
| submitter keyword: lactic acid treatment |
Contact List
| pu wang |
|---|
| contact affiliation | changzhi medical college |
| contact email | 372746529@qq.com |
| lab head | |
| pu wang |
|---|
| contact affiliation | changzhi medical college |
| contact email | 372746529@qq.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD060840 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD060840
- Label: PRIDE project
- Name: The mass spectrometry analysis detected differences in protein lactylation in B16 cells after lactic acid treatment.
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