PXD060778 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteome alterations in the human granulosa-like tumor cell line KGN after CRISPR/Cas9-based deletion of TRPV2 |
| Description | Human ovarian granulosa cell tumors (GCT) express the cation channel transient receptor potential vanilloid 2 (TRPV2) to a large percentage (95%), as detected by analyzing a panel of 72 tissue samples. To examine its role, we turned to the GCT-derived cell line KGN. CRISPR/Cas9-based deletion of TRPV2 resulted in alterations in the proteome of these cells. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-02-17 |
| AnnouncementXML | Submission_2026-02-17_01:56:07.443.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Thomas Fröhlich |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-02-13 08:29:51 | ID requested | |
| ⏵ 1 | 2026-02-17 01:56:08 | announced | |
Publication List
Keyword List
| submitter keyword: cannabidiol, granulosa cell tumors, KGN, cell death, TRPV2 |
Contact List
| Thomas Fröhlich |
|---|
| contact affiliation | Ludwig-Maximilians-Universität München Genzentrum Laboratory for Functional Genome Analysis Feodor-Lynen-Str. 25 D-81377 München |
| contact email | frohlich@genzentrum.lmu.de |
| lab head | |
| Thomas Fröhlich |
|---|
| contact affiliation | Ludwig-Maximilians-Universität München
Genzentrum
Laboratory for Functional Genome Analysis
Feodor-Lynen-Str. 25
81377 Munich |
| contact email | frohlich@genzentrum.lmu.de |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD060778 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD060778
- Label: PRIDE project
- Name: Proteome alterations in the human granulosa-like tumor cell line KGN after CRISPR/Cas9-based deletion of TRPV2
