PXD060750 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | GlycoAvatars: Bead-Coated Membrane Models for Studying the Cancer-Immune Cells Interactome |
| Description | Immature O-glycosylation, characterized by the Tn antigen expression rather than complex glycans, is prevalent in advanced solid tumors and promotes immune evasion. We developed GlycoAvatars, magnetic beads coated with plasma-membrane glycoproteins from glycoengineered cancer cell models, to identify cancer-immune cell interactomes. Through proteomics, we propose uncovered numerous membrane and intracellular proteins involved in glycan-mediated immune signaling, providing a novel high-throughput strategy for identifying potential relevant molecular nodes foreseeing therapeutic targets. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-09-07 |
| AnnouncementXML | Submission_2026-09-06_18:12:37.327.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Andreia Miranda |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-02-12 20:16:03 | ID requested | |
| ⏵ 1 | 2026-09-06 18:12:38 | announced | |
Publication List
| 10.1038/s42003-026-10274-0; |
| Miranda A, Relvas-Santos M, Louren, ç, o C, Ferreira E, Cunha DM, Palmeira C, Santos LL, Mattila PK, Ferreira JA, GlycoAvatars: bead-coated membrane models for studying the cancer-immune cells interactome. Commun Biol, 9(1):(2026) [pubmed] |
Keyword List
Contact List
| José Alexandre |
|---|
| contact affiliation | Research Center of IPO-Porto (CI-IPOP) / RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO-Porto) / Porto Comprehensive Cancer Center (P.ccc) Raquel Seruca, Porto, Portugal |
| contact email | jose.a.ferreira@ipoporto.min-saude.pt |
| lab head | |
| Andreia Miranda |
|---|
| contact affiliation | IPO-Porto |
| contact email | i37220@ipoporto.min-saude.pt |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD060750 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD060750
- Label: PRIDE project
- Name: GlycoAvatars: Bead-Coated Membrane Models for Studying the Cancer-Immune Cells Interactome
