PXD060635-1

PXD060635 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Comparative Proteomic Analysis of the Telogen-to-Anagen Transition in Cashmere Goat Secondary Hair Follicles
Description	This study investigates the proteomic changes associated with the telogen-to-anagen transition in secondary hair follicles (SHFs) of cashmere goats. Using tandem mass tag (TMT) labeling combined with LC-MS/MS, we identified 3,654 proteins, with 458 differentially expressed proteins (DEPs) between telogen and anagen phases. Key proteins such as ADAM17, SFRP1, and PPP1CA were found to play crucial roles in regulating SHF cycle transitions. These findings provide insights into the molecular mechanisms underlying cashmere fiber growth and offer potential targets for improving cashmere production.
HostingRepository	PRIDE
AnnounceDate	2025-02-13
AnnouncementXML	Submission_2025-02-12_16:46:13.943.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xiao yu Han
SpeciesList	scientific name: Capra hircus (Goat); NCBI TaxID: 9925;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-02-10 08:17:22	ID requested
⏵ 1	2025-02-12 16:46:14	announced

Publication List

10.3389/FVETS.2025.1542682;

10.3389/FVETS.2025.1542682;

Keyword List

submitter keyword: Cashmere goat Secondary hair follicles Telogen-to-anagen transition Proteomics ADAM17 SFRP1 PPP1CA LC-MS/MS TMT labeling

submitter keyword: Cashmere goat Secondary hair follicles Telogen-to-anagen transition Proteomics ADAM17 SFRP1 PPP1CA LC-MS/MS TMT labeling

Contact List

Xiaoyu Han
contact affiliation	Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot 010000, China
contact email	0141122082@mail.imu.edu.cn
lab head
Xiao yu Han
contact affiliation	+86-13327126740
contact email	0141122082@mail.imu.edu.cn
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD060635
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD060635

PRIDE project URI

Repository Record List

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