PXD060626-1

PXD060626 is an original dataset announced via ProteomeXchange.

Title	Impact of TDP-43 CR Deletion on the Synaptosome Proteome of the Mouse Brain
Description	Synaptic loss is a prominent and early pathological feature of all neurodegenerative diseases, including ALS and other TDP-43-associated neurodegenerative disorders. To investigate neuron-specific pathways affected by TDP-43 CR deletion, we conducted a quantitative mass spectrometry analysis of synaptosomes isolated from the brains of wild-type and heterozygous TDP∆CR mice.
HostingRepository	PRIDE
AnnounceDate	2026-05-22
AnnouncementXML	Submission_2026-05-22_04:03:10.269.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Masaru Miyagi
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2025-02-10 06:08:27	ID requested
⏵ 1	2026-05-22 04:03:10	announced

Dataset with its publication pending

submitter keyword: TDP-43, Mouse Brain, Synaptosome

Masaru Miyagi
contact affiliation	Case Western Reserve University
contact email	mxm356@case.edu
lab head
Masaru Miyagi
contact affiliation	Case Western Reserve University
contact email	mxm356@case.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/05/PXD060626

PRIDE project URI

• PRIDE
  1. PXD060626
     1. Label: PRIDE project
     2. Name: Impact of TDP-43 CR Deletion on the Synaptosome Proteome of the Mouse Brain