PXD060600-1

PXD060600 is an original dataset announced via ProteomeXchange.

Title	Improving glycosylation properties of PglS
Description	This work explore the optimisation of PglS to allow the improved production of glycoproteins modified with Streptococcus agalactiae associated capsule glycans.
HostingRepository	PRIDE
AnnounceDate	2026-01-23
AnnouncementXML	Submission_2026-01-23_03:30:22.511.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Nichollas Scott
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: NEWT:562;
ModificationList	complex glycosylation
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2025-02-08 22:48:07	ID requested
⏵ 1	2026-01-23 03:30:23	announced

10.1016/j.jbc.2025.110885;

Edwards RL, McAllister KN, McGuffey JC, Knoot CJ, Hooppaw AJ, Mackel JJ, Zhou B, Robinson LS, Scott NE, Harding CM, Enhancing O-linking oligosaccharyltransferase functionality through directed evolution. J Biol Chem, 302(1):110885(2026) [pubmed]

submitter keyword: glycopeptide, glycoengineering

Christian M Harding
contact affiliation	Omniose, St. Louis, MO 63110, USA
contact email	christian.harding@omniose.com
lab head
Nichollas Scott
contact affiliation	University of Melbourne
contact email	nichollas.scott@unimelb.edu.au
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD060600

PRIDE project URI

• PRIDE
  1. PXD060600
     1. Label: PRIDE project
     2. Name: Improving glycosylation properties of PglS