PXD060453-1

PXD060453 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	FFPE proteome analysis of non-cancer lesion of renal cell carcinoma
Description	To extract the molecules that correlate with kidney function and fibrosis, we performed the proteome analysis of non-cancer lesion of renal cell carcinoma in 16 patients. Proteins were extracted from FFPE slice samples and digested using the SP3 method as previously described. The digested peptide samples were analyzed by DIA-MS on a 6600 TripleTOF interfaced to Eksigent NanoLC400 system. Protein identification and quantification were performed using the library-free search function DIA-NN 1.9.2, with the UniProt human reference proteome allowing one miscleavage. The intensities of the precursors were normalized using retention time-dependent cross-run normalization. Peptides and proteins were filtered at a false discovery rate of < 1% for identification and quantification.
HostingRepository	jPOST
AnnounceDate	2025-10-21
AnnouncementXML	Submission_2025-10-21_05:33:03.953.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sumio Ohtsuki
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; O-phospho-L-serine; O-phospho-L-threonine
Instrument	instrument

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-02-04 04:05:00	ID requested
⏵ 1	2025-10-21 05:33:04	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: DIA, FFPE, renal carcinoma

submitter keyword: DIA, FFPE, renal carcinoma

Contact List

Sumio Ohtsuki
lab head
Sumio Ohtsuki
contact affiliation	Kumamoto University
dataset submitter

Full Dataset Link List

jPOST dataset URI
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jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003595/