PXD060330-1

PXD060330 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Analysis of cysteine redox state with age in flies overexpressing catalase
Description	Dysregulation of redox homeostasis has been implicated in the ageing process and the pathology of age-related diseases. To study redox signalling by hydrogen peroxide in vivo, we upregulated levels of the enzyme catalase in Drosophila.
HostingRepository	PRIDE
AnnounceDate	2025-06-30
AnnouncementXML	Submission_2025-06-29_16:09:04.855.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Andrew James
SpeciesList	scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227;
ModificationList	Applied Biosystems cleavable ICAT(TM) light
Instrument	LTQ Orbitrap

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-29 10:05:51	ID requested
⏵ 1	2025-06-29 16:09:05	announced

Publication List

Lennicke C, Bjedov I, Gr, ö, nke S, Menger KE, James AM, Castillo-Quan JI, van Leeuwen LAG, Foley A, Buricova M, Adcott J, Montoya A, Kramer HB, Shliaha PV, Logan A, Cabreiro F, Murphy MP, Partridge L, Cochem, é HM, Enhancing autophagy by redox regulation extends lifespan in Drosophila. Nat Commun, 16(1):5379(2025) [pubmed]
10.1038/s41467-025-60603-w;

Lennicke C, Bjedov I, Gr, ö, nke S, Menger KE, James AM, Castillo-Quan JI, van Leeuwen LAG, Foley A, Buricova M, Adcott J, Montoya A, Kramer HB, Shliaha PV, Logan A, Cabreiro F, Murphy MP, Partridge L, Cochem, é HM, Enhancing autophagy by redox regulation extends lifespan in Drosophila. Nat Commun, 16(1):5379(2025) [pubmed]

10.1038/s41467-025-60603-w;

Keyword List

submitter keyword: Drosophila, catalase, ageing

submitter keyword: Drosophila, catalase, ageing

Contact List

Helena M.
contact affiliation	MRC Laboratory of Medical Sciences (LMS), Du Cane Road, London
contact email	helena.cocheme@lms.mrc.ac.uk
lab head
Andrew James
contact affiliation	University of Cambridge
contact email	aj@mrc-mbu.cam.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD060330
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD060330

PRIDE project URI

Repository Record List

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