PXD060307-1

PXD060307 is an original dataset announced via ProteomeXchange.

Title	Sex-specific extracellular protein composition derived from oligodendrocyte progenitor cells (OPC) under normoxic and hyperoxic conditions
Description	Secretory proteins and extracellular vesicles (EVs) are increasingly recognized as important mediators of intercellular communication and stress response in the brain. Our analysis of the secretome from cell culture supernatants obtained after treating male and female derived primary mouse OPCs with hyperoxia (80% O2) for a 24 hours’ period, showed prominent sex-specific protein signatures.
HostingRepository	PRIDE
AnnounceDate	2025-09-29
AnnouncementXML	Submission_2025-09-28_17:09:44.423.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Elke Hammer
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-28 23:41:45	ID requested
⏵ 1	2025-09-28 17:09:45	announced

10.1002/jex2.70082;

Sunny DE, Hammer E, Michalik S, V, ö, lker U, Heckmann M, Sex-Specific Differences in the Secretome of Oligodendrocyte Progenitor Cells Post Hyperoxic Stress. J Extracell Biol, 4(9):e70082(2025) [pubmed]

submitter keyword: normoxia,Mouse, hyperoxia, OPC, secretome LC-MS/MS

Elke Hammer
contact affiliation	Dr. Elke Hammer Universitätsmedizin Greifswald Interfakultäres Institut für Genetik und Funktionelle Genomforschung Abteilung für Funktionelle Genomforschung Felix-Hausdorff-Straße 8 17487 Greifswald Germany
contact email	hammer@uni-greifswal.de
lab head
Elke Hammer
contact affiliation	Dept. of Functional Genomics
contact email	hammer@uni-greifswald.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD060307

PRIDE project URI

• PRIDE
  1. PXD060307
     1. Label: PRIDE project
     2. Name: Sex-specific extracellular protein composition derived from oligodendrocyte progenitor cells (OPC) under normoxic and hyperoxic conditions