PXD060288-1

PXD060288 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic analysis of NSD3 isoforms in prostate cancer cells Dataset2
Description	Identify interacting proteins for the protein of interest before and after DNA damage.
HostingRepository	PRIDE
AnnounceDate	2026-06-29
AnnouncementXML	Submission_2026-06-28_16:19:53.190.xml
DigitalObjectIdentifier	https://doi.org/10.6019/PXD060288
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Ben Brown
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-28 10:03:21	ID requested
⏵ 1	2026-06-28 16:19:53	announced

Publication List

10.6019/PXD060288;
Zhu S, Gao H, Jiang D, Guo G, Hou J, Han Y, Zhang C, Hu X, Indulkar S, Kloeber JA, Hu Q, Jiang Y, Zeng X, Ouyang Y, Lu J, Yin P, Luo K, Huang J, Wu Z, Chen B, Xiao H, Dragojevic S, Qin H, Zhou X, Jin J, Tu X, Wang L, Lou Z, Isoform-specific function of NSD3 in DNA replication stress confers resistance to PARP inhibitors in prostate cancer. Mol Cell, 85(14):2673-2687.e8(2025) [pubmed]
10.1016/j.molcel.2025.06.004;

10.6019/PXD060288;

Zhu S, Gao H, Jiang D, Guo G, Hou J, Han Y, Zhang C, Hu X, Indulkar S, Kloeber JA, Hu Q, Jiang Y, Zeng X, Ouyang Y, Lu J, Yin P, Luo K, Huang J, Wu Z, Chen B, Xiao H, Dragojevic S, Qin H, Zhou X, Jin J, Tu X, Wang L, Lou Z, Isoform-specific function of NSD3 in DNA replication stress confers resistance to PARP inhibitors in prostate cancer. Mol Cell, 85(14):2673-2687.e8(2025) [pubmed]

10.1016/j.molcel.2025.06.004;

Keyword List

submitter keyword: DNA Damage

submitter keyword: DNA Damage

Contact List

Zhenkun Lou
contact affiliation	Mayo Clinic, Department of Oncology
contact email	Lou.Zhenkun@mayo.edu
lab head
Ben Brown
contact affiliation	Mayo Clinic
contact email	brown.benjamin2@mayo.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD060288
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD060288

PRIDE project URI

Repository Record List

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