PXD060216-1

PXD060216 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Quantitative proteomics of FFPE-preserved cardiac specimens
Description	Archival human heart tissue, preserved as formalin-fixed, paraffin-embedded (FFPE) samples in pathology collections worldwide, represents a largely untapped resource for cardiac proteomics. This study employs a comprehensive proteomic workflow optimized for human FFPE heart tissue and leverages paired FFPE and fresh frozen (FF) tissue from the same hearts to assess its performance. We evaluate the reproducibility and depth of protein quantification across preservation methods using TMT-multiplexed measurements and further evaluate the performance of diaPASEF for profiling cardiac FFPE tissue proteomes.
HostingRepository	PRIDE
AnnounceDate	2025-08-22
AnnouncementXML	Submission_2025-08-21_19:33:46.466.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jonathan Achter
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Eclipse; timsTOF HT

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-26 13:16:34	ID requested
⏵ 1	2025-08-21 19:33:46	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: Human, FFPE, Heart

submitter keyword: Human, FFPE, Heart

Contact List

Alicia Lundby
contact affiliation	Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen
contact email	alicia.lundby@sund.ku.dk
lab head
Jonathan Achter
contact affiliation	University of Copenhagen
contact email	jonathan.achter@sund.ku.dk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD060216
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD060216

PRIDE project URI

Repository Record List

[ + ]