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PXD059980-1

PXD059980 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePhosphoproteomic analysis of hypothalamic GT1-7 neurons
DescriptionTo elucidate the mechanism of neuronal activation, we conducted a global quantitative phosphoproteomic analysis of hypothalamic neurons treated with Raptin or PBS. By COG analysis of the differentially expressed phosphorylation protein, we found obvious alterations of transport and catabolism, as well as cell motility. By conducting a KEGG analysis using phosphoproteomic data, we identified the PI3K-AKT pathway.
HostingRepositoryPRIDE
AnnounceDate2025-01-27
AnnouncementXMLSubmission_2025-01-26_22:46:37.749.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHui Peng
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListphosphorylated residue
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-01-20 08:26:44ID requested
12025-01-26 22:46:38announced
Publication List
10.1038/S41422-025-01078-8;
Keyword List
submitter keyword: phosphoprotemics,Mice, gt1-7 cells
Contact List
Xianghang Luo
contact affiliationDepartment of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, 87# Xiangya Road, Changsha, Hunan 410008, China.
contact emailxianghangluo@sina.com
lab head
Hui Peng
contact affiliationDepartment of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha, Hunan 410008, P.R. China
contact email1340568713@qq.com
dataset submitter
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Dataset FTP location
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