PXD059804-1

PXD059804 is an original dataset announced via ProteomeXchange.

Title	Integrative Omics Analysis Reveals Specific Hepatic Metabolic Adaption During Prolonged Cyclic Calorie Restriction
Description	In this study, we designed a weekly intermittent calorie restriction cycle: 50% reduction on days 1 and 4, 70% on days 2 and 3, and unrestricted eating on days 5 to 7. This pattern mimics feasible non-linear CR observed in humans. To evaluate metabolic outcomes, high-fat diets (HFD) were utilized to induce obesity and related metabolic disorders, providing a robust model for assessing the efficacy of CR interventions. Liver samples from the ad libitum (AL) control group and low-calorie (LC, Day3 of the cycle) and refeeding (RF, Day7 of the cycle) phases from the calorie-restricted group were examined via RNAseq
HostingRepository	iProX
AnnounceDate	2025-01-15
AnnouncementXML	Submission_2025-01-14_22:37:02.522.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yifan Tu
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	iodoacetamide derivatized residue
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-14 22:36:42	ID requested
⏵ 1	2025-01-14 22:37:02	announced

Dataset with its publication pending

submitter keyword: Proteomics, Metabolic Adaption, Calorie Restriction

Man Yuen Lee
contact affiliation	The Hong Kong Polytechnic University
contact email	leomylee@gmail.com
lab head
Yifan Tu
contact affiliation	Hong Kong Polytechnic University
contact email	yifan.tu@polyu.edu.hk
dataset submitter

iProX dataset URI