PXD059666-1

PXD059666 is an original dataset announced via ProteomeXchange.

Title	Hepatocyte Proteome Destabilization and Novel Targets for PFASs Unveiled through Combined Thermal Proteome Profiling and Deep Transfer Learning
Description	TPP-CCR (Thermal proteome profiling with compound concentration range TPP-CCR) identified key protein targets for three representative PFASs and a benchmark sample of staurosporine.
HostingRepository	PRIDE
AnnounceDate	2026-05-13
AnnouncementXML	Submission_2026-05-13_13:36:58.043.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zimeng Wu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-11 04:22:26	ID requested
⏵ 1	2026-05-13 13:36:58	announced

10.1016/J.JHAZMAT.2025.140458;

submitter keyword: None

Zhiqiang Fu
contact affiliation	Dalian Key Laboratory on Chemicals Risk Control and Pollution Prevention Technology
contact email	iswuzimeng@163.com
lab head
Zimeng Wu
contact affiliation	18222593531
contact email	iswuzimeng@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/05/PXD059666

PRIDE project URI

• PRIDE
  1. PXD059666
     1. Label: PRIDE project
     2. Name: Hepatocyte Proteome Destabilization and Novel Targets for PFASs Unveiled through Combined Thermal Proteome Profiling and Deep Transfer Learning