PXD059581-1

PXD059581 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	First report of natural co-infections and protein profile of Indian Major Carp, Labeo rohita
Description	A quantitative proteomics approach investigated the natural co-infected Labeo rohita kidney. A kidney proteome of L. rohita was utilized to understand the in-depth knowledge of rohu for disease mechanisms. Comparative proteome analysis was performed for our earlier submitted proteome of control and Edwardsiella tarda infected kidney using label free quantitative proteomics. High-resolution mass spectrometry was used for data using label-free quantification. Label-free proteomic analysis showed pathogenicity mechanisms related to apoptosis, lysosome, metabolic pathway, immune system and cellular response to stress in the kidney of co-infected rohu. The study specifies that co-infection for the first time in the winter season was capable of causing pathological changes in L. rohita. The initial proteome analysis of naturally co-infected rohu kidneys identified novel proteins that could aid in developing strategies for combating multiple pathogens and enhancing climate resilience in aquaculture.
HostingRepository	PRIDE
AnnounceDate	2025-10-08
AnnouncementXML	Submission_2025-10-08_10:13:43.594.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD059581
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Nevil Pinto
SpeciesList	scientific name: Labeo rohita (Indian major carp); NCBI TaxID: NEWT:84645;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-09 04:54:22	ID requested
⏵ 1	2025-10-08 10:13:44	announced

Publication List

10.1016/j.micpath.2025.107908;
10.6019/PXD059581;
Pinto N, Madhusudhana Rao B, Iqbal G, Pradeep A, Yashwanth BS, Pratapa MG, Sathiyanarayanan A, First report of natural co-infections and protein profile of Indian major carp, Labeorohita. Microb Pathog, 207():107908(2025) [pubmed]

10.1016/j.micpath.2025.107908;

10.6019/PXD059581;

Pinto N, Madhusudhana Rao B, Iqbal G, Pradeep A, Yashwanth BS, Pratapa MG, Sathiyanarayanan A, First report of natural co-infections and protein profile of Indian major carp, Labeorohita. Microb Pathog, 207():107908(2025) [pubmed]

Keyword List

submitter keyword: Co-infection, E. tarda,Labeo rohita, LC-MS/MS

submitter keyword: Co-infection, E. tarda,Labeo rohita, LC-MS/MS

Contact List

Nevil Pinto
contact affiliation	ICAR-CIFE, Mumbai
contact email	nevilpinto1@gmail.com
lab head
Nevil Pinto
contact affiliation	Mangalore University, Mangalore
contact email	nevilpinto1@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD059581
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD059581

PRIDE project URI

Repository Record List

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