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PXD059565-1

PXD059565 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAssessment of CDK4 as a serine kinase phosphorylating OGG1
DescriptionThe early studies showed the serine/threonine of OGG1 was phosphorylated by CDK4 in vitro, in our study, LC-MS/MS was performed, and Byonic engine was used to identify the precise site to be phosphorylated by CDK4.The present study discovered a high basal level of CDK4-mediated phosphorylation of OGG1 at S326, and this modification undergoes decline to resume a higher affinity with DNA for facilitating the role of OGG1 in gene transcription.
HostingRepositoryPRIDE
AnnounceDate2025-04-18
AnnouncementXMLSubmission_2025-04-18_02:34:01.511.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD059565
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterJinling Han
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListphosphorylated residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-01-08 18:44:59ID requested
12025-04-18 02:34:01announced
Publication List
10.6019/PXD059565;
Keyword List
submitter keyword: OGG1 CDK4 phosphorylation
Contact List
Professor Xueqing Ba
contact affiliationKey Laboratory of Molecular Epigenetics of the Ministry of Education (MOE), Northeast Normal University
contact emailbaxq755@nenu.edu.cn
lab head
Jinling Han
contact affiliationNortheast Normal University
contact emailhanjl681@nenu.edu.cn
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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