PXD059565-1

PXD059565 is an original dataset announced via ProteomeXchange.

Title	Assessment of CDK4 as a serine kinase phosphorylating OGG1
Description	The early studies showed the serine/threonine of OGG1 was phosphorylated by CDK4 in vitro, in our study, LC-MS/MS was performed, and Byonic engine was used to identify the precise site to be phosphorylated by CDK4.The present study discovered a high basal level of CDK4-mediated phosphorylation of OGG1 at S326, and this modification undergoes decline to resume a higher affinity with DNA for facilitating the role of OGG1 in gene transcription.
HostingRepository	PRIDE
AnnounceDate	2025-04-18
AnnouncementXML	Submission_2025-04-18_02:34:01.511.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD059565
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Jinling Han
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-08 18:44:59	ID requested
⏵ 1	2025-04-18 02:34:01	announced

10.6019/PXD059565;

submitter keyword: OGG1 CDK4 phosphorylation

Professor Xueqing Ba
contact affiliation	Key Laboratory of Molecular Epigenetics of the Ministry of Education (MOE), Northeast Normal University
contact email	baxq755@nenu.edu.cn
lab head
Jinling Han
contact affiliation	Northeast Normal University
contact email	hanjl681@nenu.edu.cn
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD059565
     1. Label: PRIDE project
     2. Name: Assessment of CDK4 as a serine kinase phosphorylating OGG1