PXD059259-1
PXD059259 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine |
| Description | To characterize the accessibility of α-syn to LPC and DOPS, we performed cross-linking experiments coupled with mass spectrometry (XL-MS). We mixed 15N-labeled and unlabeled Ac-α-syn at a 1:1 ratio and selected the cross-linked fragments containing both 15N-labeled and unlabeled Ac-α-syn to map the intermolecular cross-linking pattern. |
| HostingRepository | iProX |
| AnnounceDate | 2024-12-26 |
| AnnouncementXML | Submission_2024-12-25_23:22:34.356.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jiali Qiang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | acetylated residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-12-25 23:22:16 | ID requested | |
| ⏵ 1 | 2024-12-25 23:22:34 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: α-synuclein, N-acetylation, LPC, DOPS |
Contact List
| Yaoyang Zhang | |
|---|---|
| contact affiliation | Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences |
| contact email | zyy@sioc.com |
| lab head | |
| Jiali Qiang | |
| contact affiliation | Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences |
| contact email | qiangjl@sioc.ac.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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