PXD059152-1

PXD059152 is an original dataset announced via ProteomeXchange.

Title	Proteome profiling of Candida albicans
Description	The complex ecological dynamics between Streptococcus mutans and Candida albicans within dental plaque biofilms play a pivotal role in the etiology of dental caries. To investigate the "contact-independent" interactions between these two species, we developed a transwell co-culture system. Utilizing quantitative proteomics profiling, we aimed to dissect the impact of S. mutans on the proteomics profile of C. albicans and to uncover the molecular mechanisms that regulate their interaction. These results underscore the profound changes in the proteomics landscape of C. albicans in response to co-cultivation with S. mutans. Our study offers novel insights into the functional interplay between these predominant constituents of dental plaque, shedding light on their role in oral microbial ecology and the pathogenesis of dental caries.
HostingRepository	PRIDE
AnnounceDate	2025-01-25
AnnouncementXML	Submission_2025-01-25_00:04:56.145.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yixin Zhang
SpeciesList	scientific name: Candida albicans (Yeast); NCBI TaxID: 5476;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-22 20:39:40	ID requested
⏵ 1	2025-01-25 00:04:56	announced

Dataset with its publication pending

submitter keyword: Candida albicans, Streptococcus mutans, LC-MS/MS

Dr Peng Xian
contact affiliation	State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China (lab head)
contact email	2020224035084@stu.scu.edu.cn
lab head
Yixin Zhang
contact affiliation	15982217725
contact email	2020224035084@stu.scu.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/01/PXD059152

PRIDE project URI

• PRIDE
  1. PXD059152
     1. Label: PRIDE project
     2. Name: Proteome profiling of Candida albicans