PXD059135-2

PXD059135 is an original dataset announced via ProteomeXchange.

Title	Acetylated proteome data of young, old, FTO-knockdown and KAT8-overexpression human dermal fibroblasts
Description	Acetylated proteome data of young human dermal fibroblasts (HDFs) [Young], old HDFs [Old], FTO-knockdown HDFs [shFTO], KAT8-overexpression HDFs [KAT8] and KAT8-overexpressed HDFs after FTO deprivation [shFTO_KAT8] were analysed by LC‒MS/MS.
HostingRepository	iProX
AnnounceDate	2024-12-20
AnnouncementXML	Submission_2025-08-14_23:41:26.775.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Fan Wang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	acetylated residue
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-22 18:01:20	ID requested
1	2024-12-22 18:01:32	announced
⏵ 2	2025-08-14 23:41:27	announced	2025-08-15: Add info.

Wang F, Zhou L, Zhong Y, Cai Y, Meng X, Chen M, Mao R, Xiao X, Yi C, Guo Y, Xie H, Zhang Y, Li J, Depletion of Fat Mass and Obesity-Associated Protein (FTO) Drives Heterochromatin Loss via Lysine Acetyltransferase 8 (KAT8)-Mediated Remodeling and Spacing Factor 1 (RSF1) Acetylation in Skin Aging. MedComm (2020), 6(7):e70205(2025) [pubmed]

submitter keyword: Acetylated proteome, FTO, KAT8, young, old, human dermal fibroblasts

Ji Li
contact affiliation	Department of Dermatology, Xiangya Hospital, Central South University
contact email	liji_xy@csu.edu.cn
lab head
Fan Wang
contact affiliation	Department of Dermatology, Xiangya Hospital, Central South University
contact email	228102102@csu.edu.cn
dataset submitter

iProX dataset URI