PXD059112 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Extracellular vesicles of murine-derived epicardial derived cell line under hypoxic and normoxic environment TMT LC-MS |
| Description | Extracellular vesicles (EVs) are key players in intercellular communication. Here we show that modulating cellular environment by changing the available oxygen levels in vitro in embryonic-derived epicardial-derived cells (EPDCs) from mice we modulate their protein content. Murine EPDCs react by secreting EV with increasing content in glycolysis-related proteins when in hypoxic environment. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-12-01 |
| AnnouncementXML | Submission_2025-11-30_16:31:50.303.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jorge Cobos |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | TMT6plex-126 reporter+balance reagent acylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-12-21 04:29:06 | ID requested | |
| ⏵ 1 | 2025-11-30 16:31:51 | announced | |
Publication List
| Oliveira CC, C, ó, rdoba J, Pearson JR, Guruceaga E, Mar, í, n-Sede, ñ, o E, L, ó, pez-Moreno M, Guadix JA, Garc, í, a-Caballero M, P, é, rez-Pomares JM, Ruiz-Villalba A, Revealing the complexity of the epicardial secretome. Sci Rep, 15(1):41197(2025) [pubmed] |
| 10.1038/s41598-025-24980-y; |
Keyword List
| submitter keyword: Exosomes |
| hypoxia |
| normoxia |
| EPDC |
Contact List
| Jorge Cobos Figueroa |
|---|
| contact affiliation | Departamento de Biología Animal, Facultad de Ciencias, Universidad de Málaga |
| contact email | jcobosf@uma.es |
| lab head | |
| Jorge Cobos |
|---|
| contact affiliation | PhD Student at UMA |
| contact email | jcobosf@uma.es |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD059112 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD059112
- Label: PRIDE project
- Name: Extracellular vesicles of murine-derived epicardial derived cell line under hypoxic and normoxic environment TMT LC-MS
