PXD058940-1

PXD058940 is an original dataset announced via ProteomeXchange.

Title	COMPARATIVE PROTEOME ANALYSIS OF BIKANERI AND JAISALMERI CAMEL MILK IN INDIA
Description	Camel milk is considered one of the most valuable food sources for nomadic people in arid and semi-arid areas and has also been consumed as a natural adjuvant for managing a variety of human diseases for centuries due to its nutritional values and extraordinary medicinal properties. A total of 180 milk samples were collected from Bikaneri and Jaisalmeri camels during various seasons in the Jodhpur and Sikar districts of Rajasthan for the proteomics study. Protein profiling of camel milk was done by LC-MS/MS. The protein pellets were prepared from 50 mL of pooled raw milk. The trypsinization and clean-up protocol was performed using standard methods. Then, Mass spectrometric analysis of peptide mixtures was performed using the EASY-nLC 1200 system coupled to a Thermo Fisher-Q Exactive equipped with a nanoelectrospray ion source. All samples were processed and analyzed with Proteome Discoverer (v2.4) against the Uniprot camel reference proteome database. A total of 704 protein groups were identified in the milk of Bikaneri and Jaisalmeri camels on the Uniprot Camelus dromedarius Database. There were 21 (3%) and 17 (2.4%) unique protein groups with 666 (94.6%) common proteins in the milk of Bikaneri and Jaisalmeri, respectively. In addition, 687 (97%) and 683 (98%) specific proteins were found in Bikaneri and Jaisalmeri camel milk, respectively. The camel casein components (CNs) were found as αs1-CN, αs2-CN, β- CN and κ-CN. Whey protein such as β-lactoglobulin was not found in the camel milk but α- lactalbumin was abundant. Breed variation was less observed because only 18 significantly expressed proteins were obtained in the milk of the Bikaneri and Jaisalmeri camel breeds.
HostingRepository	PRIDE
AnnounceDate	2025-09-22
AnnouncementXML	Submission_2025-09-22_04:45:33.096.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Barkha Gupta
SpeciesList	scientific name: Camelus dromedarius (Dromedary) (Arabian camel); NCBI TaxID: 9838;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-17 05:25:02	ID requested
⏵ 1	2025-09-22 04:45:33	announced

Dataset with its publication pending

submitter keyword: Jaisalmeri camels, Medicinal properties,Mass Spectrometry, Protein Profiling, Camel milk, Proteomics, Bikaneri camels, LC-MS/MS

Dr. Barkha
contact affiliation	Dr. Barkha Gupta Principal Investigator, M-RAJUVAS Project IFBA Certified Professional Assistant Professor (Veterinary Biochemistry) Incharge, IUMS & IT Operations Post Graduate Institute of Veterinary Education & Research (PGIVER), Jaipur (RAJUVAS, Bikaner), India
contact email	drbgvet@gmail.com
lab head
Barkha Gupta
contact affiliation	Assistant Professor (Senior Scale)
contact email	drbgvet@gmail.com
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD058940
     1. Label: PRIDE project
     2. Name: COMPARATIVE PROTEOME ANALYSIS OF BIKANERI AND JAISALMERI CAMEL MILK IN INDIA