PXD058790-1

PXD058790 is an original dataset announced via ProteomeXchange.

Title	Multi-omics analysis combined with the Nephroseq database reveals that FN1 and three other genes are closely related to renal function in diabetic nephropathy.
Description	Diabetic nephropathy is a serious late chronic complication of type 2 diabetes and a major cause of end-stage renal disease. In order to better understand the molecular mechanisms of kidney lesions, we examined the mRNA and protein levels of mouse kidney to reveal the changes occurring in the kidney tissue of diabetes-associated kidney injury at the molecular level, to provide a theoretical basis for drug treatment.
HostingRepository	PRIDE
AnnounceDate	2025-10-20
AnnouncementXML	Submission_2025-10-19_17:36:31.379.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	ling deng
SpeciesList	scientific name: Arabidopsis thaliana (Mouse-ear cress); NCBI TaxID: NEWT:3702;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-11 16:23:10	ID requested
⏵ 1	2025-10-19 17:36:32	announced

Deng L, Yan F, Feng C, Yang Q, Multi-Omics Analysis and Nephroseq Database of Genes Related to Kidney Function in Diabetic Nephropathy Patients to Predict Potential Target Drugs. Diabetes Metab Syndr Obes, 18():3781-3794(2025) [pubmed]

10.2147/dmso.s526696;

submitter keyword: proteomics,Transcriptomics, liraglutide, type 2 diabetes, empagliflozin, diabetic nephropathy

First Name: Ling ,Last Name: Deng
contact affiliation	Nanxishan Hospital of Guangxi Zhuang Autonomous Region
contact email	2532594060@qq.com
lab head
ling deng
contact affiliation	Nanxishan Hospital of Guangxi Zhuang Autonomous Region
contact email	2532594060@qq.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD058790

PRIDE project URI

• PRIDE
  1. PXD058790
     1. Label: PRIDE project
     2. Name: Multi-omics analysis combined with the Nephroseq database reveals that FN1 and three other genes are closely related to renal function in diabetic nephropathy.