PXD058754-1
PXD058754 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Dietary secoisolariciresinol diglucoside metabolites enhance immunity and suppress colorectal cancer through inhibiting the SYK/NF-κB/MMP3/Decorin axis |
| Description | We established a subcutaneous tumor model in BALB/c nude mice using the HCT116 cell line and administered secoisolariciresinol (SECO) orally to one group for 18 days. Tumor tissues were then collected for 4D-label-free proteomic analysis. |
| HostingRepository | iProX |
| AnnounceDate | 2024-12-11 |
| AnnouncementXML | Submission_2025-09-29_18:51:22.008.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Xinghua Zhang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-12-10 22:56:51 | ID requested | |
| ⏵ 1 | 2025-09-29 18:51:22 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Animal lignans, Colorectal cancer, Anti-cancer, Tumor immunity |
Contact List
| Shulin Liu | |
|---|---|
| contact affiliation | Harbin Medical University |
| contact email | slliu@hrbmu.edu.cn |
| lab head | |
| Xinghua Zhang | |
| contact affiliation | Harbin Medical University |
| contact email | zxh_0707@hrbmu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |




