PXD058690-1

PXD058690 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Cerebrovascular proteome changes with mucin-domain glycoprotein degradation and core 1 mucin-type O-glycan downregulation
Description	Mucin-domain glycoproteins are overlooked yet crucial components of the brain endothelial glycocalyx, playing essential roles in maintaining cerebrovascular integrity and function. Dysregulation of these glycoproteins has been implicated in aging and neurodegenerative disease, including Alzheimer’s disease. In this study, we used both enzymatic and genetic techniques to investigate the influence of mucin-domain glycoproteins on cerebrovascular biology.
HostingRepository	PRIDE
AnnounceDate	2024-12-17
AnnouncementXML	Submission_2024-12-17_10:50:34.930.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sophia Shi
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	iodoacetamide derivatized residue
Instrument	timsTOF Pro

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-09 01:22:46	ID requested
⏵ 1	2024-12-17 10:50:35	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: Vasculature, TimsTOF,Mouse, Brain, LC-MS/MS

submitter keyword: Vasculature, TimsTOF,Mouse, Brain, LC-MS/MS

Contact List

Tony Wyss-Coray
contact affiliation	Department of Neurology and Neurological Sciences, Stanford University, United States
contact email	twc@stanford.edu
lab head
Sophia Shi
contact affiliation	Stanford University
contact email	smshi@stanford.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/12/PXD058690
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/12/PXD058690

PRIDE project URI

Repository Record List

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