PXD058626-1

PXD058626 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The MUC5B promoter variant results in proteomic changes in the non-fibrotic lung
Description	The gain-of-function MUC5B promoter varaint is the dominant risk for IPF development. Herein, we performed laser capture microdissection coupled mass spectrometry to isolate the characteristic histopathological lesions of IPF, the normal-appearing alveoli/small airways, and epithelium overlying fibroblastic foci. The captured samples were subject to mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2025-06-13
AnnouncementXML	Submission_2025-06-13_06:33:01.722.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	JEREMY HERRERA
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	timsTOF SCP

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-05 12:27:36	ID requested
⏵ 1	2025-06-13 06:33:02	announced

Publication List

10.1172/JCI.INSIGHT.189636;

10.1172/JCI.INSIGHT.189636;

Keyword List

submitter keyword: Human, IPF, Lung, Fibrosis, MUC5B

submitter keyword: Human, IPF, Lung, Fibrosis, MUC5B

Contact List

Jeremy Herrera
contact affiliation	University of Colorado, Anschutz Medical Campus
contact email	jeremy.herrera@cuanschutz.edu
lab head
JEREMY HERRERA
contact affiliation	University of Colorado, Anschutz Medical Campus
contact email	jeremy.herrera@cuanschutz.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD058626
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD058626

PRIDE project URI

Repository Record List

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