PXD058527 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | SSR4 deficiency in B-cell reshapes the inflammatory microenvironment |
| Description | The development and differentiation of infiltrating B cells influence the structure of the immune microenvironment (TIME). We aimed to unveil the impact of regulating B cell development and antibodies secretion by glycosylation modification-associated protein SSR4 on the formation of IME structures and anti-tumor immunity in colorectal cancer (CRC) |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-09-07 |
| AnnouncementXML | Submission_2026-09-06_16:34:20.863.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | 薇 赵 |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | LTQ Orbitrap Elite |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-12-03 05:06:48 | ID requested | |
| ⏵ 1 | 2026-09-06 16:34:21 | announced | |
Publication List
| 10.1002/advs.75790; |
| Zhao W, Zhao Y, Li H, Yang B, Lu S, Fu X, Zhang C, Chen Y, Bian X, Ma X, Yang X, Wang B, Fang Y, Yang L, Zhao Y, Zhao S, SSR4 Sustains Tertiary Lymphoid Structures by Regulation Quality Control of N-linked Glycosylation During B-cell Differentiation Into Plasmacyte in Colorectal Cancer. Adv Sci (Weinh), 13(46):e75790(2026) [pubmed] |
Keyword List
| submitter keyword: Mouse，B cells,SSR4 deficiency |
Contact List
| Shuli Zhao |
|---|
| contact affiliation | Nanjing First Hospital |
| contact email | shulizhao79@njmu.edu.cn |
| lab head | |
| 薇 赵 |
|---|
| contact affiliation | Nanjing First Hospital |
| contact email | zhaowei_njmu@163.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD058527 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD058527
- Label: PRIDE project
- Name: SSR4 deficiency in B-cell reshapes the inflammatory microenvironment
