PXD058425-1

PXD058425 is an original dataset announced via ProteomeXchange.

Title	Mitofusin 2 displays fusion-independent roles in proteostasis surveillance
Description	Whole cell proteome of WT, MFN1 KO, MFN2 KO, MFN1 KO stably expressing MFN1 or MFN2KO stably expressing MFN2
HostingRepository	PRIDE
AnnounceDate	2025-05-07
AnnouncementXML	Submission_2025-05-07_05:39:55.946.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Prerana Wagle
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-29 14:12:27	ID requested
⏵ 1	2025-05-07 05:39:56	announced

Joaquim M, Altin S, Bulimaga MB, Sim, õ, es T, Nolte H, Bader V, Franchino CA, Plouzennec S, Szczepanowska K, Marchesan E, Hofmann K, Kr, ü, ger M, Ziviani E, Trifunovic A, Chevrollier A, Winklhofer KF, Motori E, Odenthal M, Escobar-Henriques M, Mitofusin 2 displays fusion-independent roles in proteostasis surveillance. Nat Commun, 16(1):1501(2025) [pubmed]

10.1038/s41467-025-56673-5;

submitter keyword: mitochondria, protein quality control, MFN2

Mafalda Escobar
contact affiliation	Institute for Genetics, University of Cologne
contact email	Mafalda.Escobar@uni-koeln.de
lab head
Prerana Wagle
contact affiliation	CECAD Research Center
contact email	proteomics-facility@uni-koeln.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD058425

PRIDE project URI

• PRIDE
  1. PXD058425
     1. Label: PRIDE project
     2. Name: Mitofusin 2 displays fusion-independent roles in proteostasis surveillance