PXD058306-1

PXD058306 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	LC-MS/MS data of specific proteins involved 4-HNE modification in bone formation
Description	To elucidate the specific proteins involved in bone formation that are modified by 4-HNE, we performed LC-MS-based proteomics analysis. This approach identified several candidate proteins, including MAP kinase-activated protein kinase 3 (MAPK3), plastin-3 (PLS3), and integrin-linked protein kinase (ILK), all of which are implicated in bone formation or osteoblast differentiation. Notably, 4-HNE-modified ILK was significantly elevated in the GPX4-inhibited group (RSL3 treatment) compared to the control group.
HostingRepository	MassIVE
AnnounceDate	2024-11-29
AnnouncementXML	Submission_2024-11-29_07:23:26.280.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	GONGHAIBIAO
SpeciesList	scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090;
ModificationList	unknown modification
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-26 21:41:56	ID requested
⏵ 1	2024-11-29 07:23:26	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Phospholipid peroxidation, Osteoporosis, 4-HNE modification, DatasetType:Proteomics

submitter keyword: Phospholipid peroxidation, Osteoporosis, 4-HNE modification, DatasetType:Proteomics

Contact List

Rong-Rong He
contact affiliation	Jinan university
contact email	rongronghe@jnu.edu.cn
lab head
GONGHAIBIAO
contact affiliation	Jinan university
contact email	haibiaojnu@163.com
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v07/MSV000096541/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v07/MSV000096541/