PXD058303-1

PXD058303 is an original dataset announced via ProteomeXchange.

Title	ATAD2 is a Potential Immunotherapy Target for Patients with Small Cell Lung Cancer Harboring HLA-A*0201
Description	To identify the immune peptides in SCLC tumour cells that can be processed and presented by HLA-I, we performed LC–MS/MS analysis on 11 SCLC cell lines, representing the heterogeneity of SCLC subtypes. Ten of the cell lines were confirmed positive for HLA-I, and one was HLA-I-deficient. To analyse cell surface antigens on the HLA-I-deficient cells, PBMCs isolated from healthy blood donors were treated with DMS53 cell lysate and matured into DCs to present the tumour cell antigens.
HostingRepository	iProX
AnnounceDate	2024-11-26
AnnouncementXML	Submission_2025-02-04_20:40:37.505.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yuan Li
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-26 19:19:42	ID requested
⏵ 1	2025-02-04 20:40:37	announced
2	2025-05-19 00:28:08	announced	2025-05-19: Add Publication.

Dataset with its publication pending

submitter keyword: liquid chromatography–tandem mass spectrometry analysis, Immunopeptidomics, HLA-peptide complexes

Jie Wang
contact affiliation	Chinese Academy of Medical Sciences Peking Union Medical College, Beijing
contact email	zlhuxi@163.com
lab head
Yuan Li
contact affiliation	Chinese Academy of Medical Sciences Peking Union Medical College, Beijing
contact email	yuanli10100801@163.com
dataset submitter

iProX dataset URI