PXD058261-1

PXD058261 is an original dataset announced via ProteomeXchange.

Title	The effects of enzalutamide on androgen-dependent and androgen-independent prostate cancer cells.
Description	To investigate the mechanisms of drug resistance and castration resistance in prostate cancer, we performed proteomic sequencing on androgen-dependent prostate cancer cells (LNCaP) and androgen-independent cells (AI) treated with enzalutamide.
HostingRepository	iProX
AnnounceDate	2024-11-26
AnnouncementXML	Submission_2025-03-23_18:48:33.238.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yibo Meng
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-25 20:16:23	ID requested
⏵ 1	2025-03-23 18:48:34	announced

Meng Y, Ge J, Zhou C, Ma H, Chen C, Zhou Y, Hu X, Xu Y, Wang X, Shi G, Yu W, Zhang J, Elevated VRK1 levels after androgen deprivation therapy promote prostate cancer progression by upregulating YAP1 expression. J Cancer Res Clin Oncol, 151(3):116(2025) [pubmed]

submitter keyword: enzalutamide, prostate cancer, LNCaP

Guowei Shi
contact affiliation	The Fifth People's Hospital of Shanghai, Fudan University
contact email	dr.sgw@189.cn
lab head
Yibo Meng
contact affiliation	The Fifth People's Hospital of Shanghai, Fudan University
contact email	mengyibo9@163.com
dataset submitter

iProX dataset URI