PXD058046-1

PXD058046 is an original dataset announced via ProteomeXchange.

Title	Identification of in cellulo Uranyl-Binding Proteins in Arabidopsis Cells
Description	Uranium (U) is a naturally occurring radionuclide. The redistribution of U in the environment is primarily driven by anthropogenic activities, including mining operations, the nuclear industry, military activities, and soil fertilization. Local accumulation of U can pose potential risks to ecosystems, agricultural systems, and ultimately human health. Although U is not essential for plants, yet they take it up from the soil and incorporate it into their biomass. This eventually enters the food chain, posing a significant health risk to humans. To identify proteins that could be cellular targets for U in planta, we used a metalloproteomic approach combining column chromatographic fractionation analyses with protein identification by high-resolution mass spectrometry (MS)-based shotgun proteomics.
HostingRepository	PRIDE
AnnounceDate	2025-08-01
AnnouncementXML	Submission_2025-08-01_05:20:26.563.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD058046
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Yohann Couté
SpeciesList	scientific name: Arabidopsis thaliana (Mouse-ear cress); NCBI TaxID: 3702;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-19 07:06:16	ID requested
⏵ 1	2025-08-01 05:20:27	announced

10.1016/j.jhazmat.2025.139163;

Revel BH, Favier A, Martin-Laffon J, Vallet A, Przybyla-Toscano J, Brugi, è, re S, Cout, é Y, Diemer H, Cianf, é, rani S, Rabilloud T, Bourguignon J, Brutscher B, Ravanel S, Alban C, Identification of uranyl-binding proteins in Arabidopsis thaliana cells exposed to uranium: Insights from a metalloproteomic analysis and characterization of Glycine-Rich RNA-binding protein 7 (GRP7). J Hazard Mater, 495():139163(2025) [pubmed]

10.6019/PXD058046;

submitter keyword: Arabidopsis, uranium-binding proteins, metalloproteomics, nanoLC-MS/MS

Yohann Couté
contact affiliation	EDyP
contact email	yohann.coute@cea.fr
lab head
Yohann Couté
contact affiliation	EDyP
contact email	yohann.coute@cea.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD058046

PRIDE project URI

• PRIDE
  1. PXD058046
     1. Label: PRIDE project
     2. Name: Identification of in cellulo Uranyl-Binding Proteins in Arabidopsis Cells