PXD057952-1

PXD057952 is an original dataset announced via ProteomeXchange.

Title	To identify the phenol soluble modulins whose production are primarily affected by SarZ in Staphylococcus epidermidis
Description	Phenol-soluble modulins (PSMs) are a class of short, amphipathic, α-helical peptides, which have strong cytolytic effects toward leukocytes and erythrocytes in S. epidermidis. SarZ is a key transcriptional regulator required for the expression of virulence factors. To determine whether the production of PSMs is under the control of SarZ, a sarZ deletion mutant strain was generated. Through butanol extraction of the spent medium and subsequent HPLC-MS/MS analysis, the amounts of PSMs were compared between the sarZ mutant and its parent strain.
HostingRepository	PRIDE
AnnounceDate	2024-12-05
AnnouncementXML	Submission_2024-12-04_17:04:02.926.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tao Zhu
SpeciesList	scientific name: Staphylococcus epidermidis RP62A; NCBI TaxID: 176279;
ModificationList	formylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Exploris 240

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-15 18:59:47	ID requested
⏵ 1	2024-12-04 17:04:03	announced

Anderson M, The US Bureau of the Census in the nineteenth century. Soc Hist Med, 4(3):497-513(1991) [pubmed]

10.1093/shm/4.3.497;

submitter keyword: phenol soluble modulins,Staphylococcus epidermidis, LC-MS/MS

Tao Zhu
contact affiliation	Department of Medical Microbiology and Immunology,Wannan medical college
contact email	zhutao@wnmc.edu.cn
lab head
Tao Zhu
contact affiliation	Wannan medical college
contact email	zhutao@wnmc.edu.cn
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD057952
     1. Label: PRIDE project
     2. Name: To identify the phenol soluble modulins whose production are primarily affected by SarZ in Staphylococcus epidermidis