PXD057925-1

PXD057925 is an original dataset announced via ProteomeXchange.

Title	Intact HepG2 CHKA target engagement with CETSA
Description	To confirm UNC638 and UNC737 target engagement to CHKA in live cells.
HostingRepository	PRIDE
AnnounceDate	2025-01-28
AnnouncementXML	Submission_2025-01-28_01:19:50.540.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tuomas Tolvanen
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-15 03:38:23	ID requested
⏵ 1	2025-01-28 01:19:51	announced

10.1002/anie.202420149;

Bauer LG, Ward JA, D, í, az-S, á, ez L, Sundstr, ö, m Y, Tolvanen T, Alarc, ó, n Barrera JC, Kostidis S, Rogers CM, Panagakou I, Singh U, Rothweiler EM, Gonzalez Orta A, Kaniskan H Ü, Hu J, Jin J, Sievers S, Waldmann H, Giera M, Sundstr, ö, m M, Berg L, Huber KVM, Phenomics-Based Discovery of Novel Orthosteric Choline Kinase Inhibitors. Angew Chem Int Ed Engl, 64(7):e202420149(2025) [pubmed]

submitter keyword: CETSA, Human, CHKA

Daniel Martinez-Molina
contact affiliation	Chief Scientific Offiser, Pelago Bioscience AB
contact email	daniel@pelagobio.com
lab head
Tuomas Tolvanen
contact affiliation	Pelago Bioscience AB
contact email	tuomas.tolvanen@pelagobio.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/01/PXD057925

PRIDE project URI

• PRIDE
  1. PXD057925
     1. Label: PRIDE project
     2. Name: Intact HepG2 CHKA target engagement with CETSA