PXD057922-2

PXD057922 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	FLAG-IP-MS analyses of novel oxidative stress responsive translation factors
Description	We identified translation-related factors with significantly elevated cysteine oxidation upon MND treatment by our redox proteomics method DIALRP. Notably, our data demonstrate that the inhibition of such as EIF2, EIF6, and EEF2 complex formation due to oxidative stress occurs during the cellular response of translational inhibition.
HostingRepository	jPOST
AnnounceDate	2025-07-31
AnnouncementXML	Submission_2025-07-31_22:52:24.293.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Daiki Kobayashi
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; unknown modification
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-15 01:12:32	ID requested
1	2025-07-31 01:45:37	announced
⏵ 2	2025-07-31 22:52:25	announced	2025-08-01: Updated PubMed.

Publication List

Kobayashi D, Takami T, Matsumoto M, Data-Independent Acquisition (DIA)-Based Label-Free Redox Proteomics (DIALRP) Identifies Prominent Cysteine Oxidations in Translation Machinery in Prostate Cancer Cells Under Oxidative Stress. J Proteome Res, 24(9):4597-4610(2025) [pubmed]

Kobayashi D, Takami T, Matsumoto M, Data-Independent Acquisition (DIA)-Based Label-Free Redox Proteomics (DIALRP) Identifies Prominent Cysteine Oxidations in Translation Machinery in Prostate Cancer Cells Under Oxidative Stress. J Proteome Res, 24(9):4597-4610(2025) [pubmed]

Keyword List

submitter keyword: oxidative stress, translation factors, FLAG-IP

submitter keyword: oxidative stress, translation factors, FLAG-IP

Contact List

Masaki Matsumoto
lab head
Daiki Kobayashi
contact affiliation	Niigata University
dataset submitter

Full Dataset Link List

jPOST dataset URI
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jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003470/