PXD057812-1

PXD057812 is an original dataset announced via ProteomeXchange.

Title	Synovial Fluid Alpha-2-Macroglobulin, Gelsolin, and Lubricin Distinguish Between Osteoarthritic and Healthy Equine Joints
Description	This project was designed to use liquid chromatography-tandem mass spectrometry (LC-MS/MS) to define the synovial fluid proteome in horses with and without carpal OA. This study was conceived to identify differentially regulated proteins in mild-moderate carpal joint disease compared to healthy joints.
HostingRepository	PRIDE
AnnounceDate	2025-09-15
AnnouncementXML	Submission_2025-09-14_16:19:58.716.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Qin Fu
SpeciesList	scientific name: Equus caballus (Horse); NCBI TaxID: 9796;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-12 13:52:52	ID requested
⏵ 1	2025-09-14 16:19:59	announced

Secor EJ, Womack SJ, Ysebaert MP, Colville MJ, Reesink HL, Synovial fluid alpha-2-macroglobulin, gelsolin and lubricin distinguish between osteoarthritic and healthy equine joints. Equine Vet J, ():(2025) [pubmed]

10.1111/evj.14511;

submitter keyword: horse, lubricin, alpha-2-macroglobulin, arthritis, gelsolin, carpus

Qin Fu
contact affiliation	Cornell University
contact email	qf44@cornell.edu
lab head
Qin Fu
contact affiliation	Cornell University
contact email	qf44@cornell.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD057812

PRIDE project URI

• PRIDE
  1. PXD057812
     1. Label: PRIDE project
     2. Name: Synovial Fluid Alpha-2-Macroglobulin, Gelsolin, and Lubricin Distinguish Between Osteoarthritic and Healthy Equine Joints