PXD057790 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Identification of PRRC2B methylation sites |
| Description | It was hypothesized that the human PRRC2B protein (Uniprot accession Q5JSZ5) interacts with its RNA binding targets via methylated arginines. The protein contains at least two RG rich motifs (residues 1061-1080, and 1104-1124), in which the arginines are hypothesized to be methylated. The goal of the experiment was to identify such methylated PRRC2B arginines. To get a wide coverage of the RG rich domains, an immuno-precipitation experiment was performed, followed by digestion with chymotrypsin and LC-MS/MS analysis. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-10-26 |
| AnnouncementXML | Submission_2025-10-26_04:18:34.151.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Alon Savidor |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | methylated arginine; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-11-12 05:19:59 | ID requested | |
| ⏵ 1 | 2025-10-26 04:18:34 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: methylation, PRRC2B, IP, chymotrypsin,DAP5, LC-MS/MS |
Contact List
| Prof. Adi |
|---|
| contact affiliation | Department of Molecular Genetics Faculty of Biochemistry Weizmann Institute of Science Rehovot, Israel |
| contact email | adi.kimchi@weizmann.ac.il |
| lab head | |
| Alon Savidor |
|---|
| contact affiliation | The Weizmann Institute of Science |
| contact email | alon.savidor@weizmann.ac.il |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD057790 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD057790
- Label: PRIDE project
- Name: Identification of PRRC2B methylation sites
