PXD057687 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Human colorectal cancer and wildtype LC-MSMS |
| Description | This project introduces **NARWHAL**, a versatile platform and pipeline for neoantigen discovery in cancer immunotherapy. NARWHAL identifies mutated tumor-specific antigens (mTSAs) and aberrantly expressed antigens (aeTSAs) by integrating somatic mutation data, gene expression levels, and MHC binding affinity predictions. The platform’s unique k-mer profiling technique identifies aeTSAs from coding and noncoding regions, enabling comprehensive annotation. Validated with clinical data, NARWHAL advances neoantigen identification, supporting personalized cancer treatments by uncovering novel immunotherapy targets and enhancing therapeutic precision. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-01-28 |
| AnnouncementXML | Submission_2026-01-28_11:08:59.934.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Chia-Yu Sung |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-11-08 16:23:33 | ID requested | |
| ⏵ 1 | 2026-01-28 11:09:00 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
Contact List
| Chien-Yueh Lee |
|---|
| contact affiliation | Artificial Intelligence, Innovation Frontier Institute of Research for Science and Technology, and the Department of Electrical Engineering, College of Electrical Engineering and Computer Science, National Taiwan University of Technology, Taiwan |
| contact email | leecy@ntut.edu.tw |
| lab head | |
| Chia-Yu Sung |
|---|
| contact affiliation | National Taiwan University |
| contact email | joyce7625e5@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD057687 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD057687
- Label: PRIDE project
- Name: Human colorectal cancer and wildtype LC-MSMS
