PXD057641-2
PXD057641 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Dysregulated ac4C modification of mRNA in a mouse model of early-stage Alzheimer's disease |
| Description | To investigate proteomic changes in the hippocampus associated with early AD, we performed a comparative analysis of 3-month-old WT and 5×FAD mice. |
| HostingRepository | iProX |
| AnnounceDate | 2024-11-07 |
| AnnouncementXML | Submission_2025-08-20_19:27:19.098.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Danhong Wu |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-11-07 18:23:57 | ID requested | |
| 1 | 2025-07-10 19:19:38 | announced | |
| ⏵ 2 | 2025-08-20 19:27:19 | announced | 2025-08-21: Add info. |
Publication List
| Ji HN, Zhou HQ, Qie JB, Lu WM, Gao HT, Wu DH, Dysregulated ac4C modification of mRNA in a mouse model of early-stage Alzheimer's disease. Cell Biosci, 15(1):45(2025) [pubmed] |
Keyword List
| submitter keyword: ac4C acetylation, Alzheimer’s disease, hippocampus |
Contact List
| Danhong Wu | |
|---|---|
| contact affiliation | Shanghai Fifth People's Hospital, Fudan University |
| contact email | danhongwu@fudan.edu.cn |
| lab head | |
| Danhong Wu | |
| contact affiliation | Shanghai Fifth People's Hospital, Fudan University |
| contact email | danhongwu@fudan.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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