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PXD057541-1

PXD057541 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSmall molecule-induced alterations of protein polyubiquitination revealed by mass-spectrometric ubiquitome analysis
DescriptionMammalian cells were treated with different small molecules which interfere with the ubiquitin system. After cell lysis, ubiquitinated proteins were enriched with biotin-tagged TUBE, digested with Trypsin/LysC and labelled with TMT. Peptides were fractionated at high pH before nano-LC-MS/MS analysis.
HostingRepositoryMassIVE
AnnounceDate2025-06-06
AnnouncementXMLSubmission_2025-06-06_04:14:20.865.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterPetra Janning
SpeciesList scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-11-05 07:53:09ID requested
12025-06-06 04:14:21announced
Publication List
no publication
Keyword List
submitter keyword: Drug discovery, Ubiquitin proteasome system, Protein degradation, TMT labeling, Deubiquitinase inhibitors, DatasetType:Proteomics
Contact List
Petra Janning
contact affiliationMPI of Molecular Physiology
contact emailpetra.janning@mpi-dortmund.mpg.de
lab head
Petra Janning
contact affiliationMPI f�r molekulare Physiologie
contact emailpetra.janning@mpi-dortmund.mpg.de
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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