PXD057469-1

PXD057469 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic Analysis of LncPTEN1 RNA Pulldown in Lung Cancer Cells Using LC-MS/MS
Description	This study aims to identify the molecular function of LncPTEN1 in lung cancer and explore its associated proteins and pathways. Using RNA pulldown coupled with mass spectrometry, we investigated the protein interactions of LncPTEN1 in A549 lung cancer cells. The experiment included three biological replicates with samples 1, 2, 3 as control group and samples 4, 5, 6 as LncPTEN1 overexpression group. The study revealed potential binding partners including Vimentin and Trim16, providing insights into the regulatory mechanisms of LncPTEN1 in lung cancer metastasis.
HostingRepository	PRIDE
AnnounceDate	2025-06-23
AnnouncementXML	Submission_2025-06-22_16:05:05.141.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zichu Shen
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	4800 Proteomics Analyzer

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-03 21:00:23	ID requested
⏵ 1	2025-06-22 16:05:06	announced

Publication List

10.1016/j.ncrna.2025.05.011;
Shen Z, Zhong A, Zhang C, Tang X, Zhao X, Hou Z, Liang H, Yin Y, , suppresses lung cancer metastasis through the regulation of EMT progress. Noncoding RNA Res, 14():25-37(2025) [pubmed]

10.1016/j.ncrna.2025.05.011;

Shen Z, Zhong A, Zhang C, Tang X, Zhao X, Hou Z, Liang H, Yin Y, , suppresses lung cancer metastasis through the regulation of EMT progress. Noncoding RNA Res, 14():25-37(2025) [pubmed]

Keyword List

submitter keyword: Trim16, Vimentin, Mass Spectrometry,LncPTEN1, A549, Proteomics, RNA Pulldown

submitter keyword: Trim16, Vimentin, Mass Spectrometry,LncPTEN1, A549, Proteomics, RNA Pulldown

Contact List

Zichu Shen
contact affiliation	Peking University
contact email	949618250@qq.com
lab head
Zichu Shen
contact affiliation	Peking University
contact email	949618250@qq.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD057469
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD057469

PRIDE project URI

Repository Record List

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