PXD057452-1

PXD057452 is an original dataset announced via ProteomeXchange.

Title	Oceanic photosynthesis is directly affected by cyanophage NblA proteins - whole cell proteome changes
Description	Marine picocyanobacteria are abundant and globally significant photosynthetic organisms that coexist in the ocean with cyanophages, viruses that infect cyanobacteria. Cyanophages carry auxiliary metabolic genes acquired from their hosts, which are thought to reprogram host metabolism to benefit the phage. One such gene is nblA, found across multiple cyanophage families. In cyanobacteria, nblA is responsible for triggering the proteolytic degradation of the phycobilisome—the large light-harvesting complex essential for photosynthesis—under nutrient deprivation. In this study, we characterized the proteomic changes in Synechococcus sp. strain WH8109 following infection with wild-type cyanophage S-TIP37, a T7-like phage isolated from the Red Sea, and compared these changes to those observed with an S-TIP37 mutant lacking the nblA gene.
HostingRepository	PRIDE
AnnounceDate	2025-10-06
AnnouncementXML	Submission_2025-10-06_05:25:07.658.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Oded Kleifeld
SpeciesList	scientific name: Synechococcus sp. WH 8109; NCBI TaxID: NEWT:166314;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-02 12:23:32	ID requested
⏵ 1	2025-10-06 05:25:08	announced

10.1038/S41586-025-09656-X;

submitter keyword: Phycobilisome, Synechococcus sp.,Cyanophage, NblA

Oded Kleifeld
contact affiliation	Faculty of Biology, Technion – Israel Institute of Technology
contact email	okleifeld@technion.ac.il
lab head
Oded Kleifeld
contact affiliation	Technion
contact email	okleifeld@technion.ac.il
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD057452
     1. Label: PRIDE project
     2. Name: Oceanic photosynthesis is directly affected by cyanophage NblA proteins - whole cell proteome changes