PXD057369-1

PXD057369 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Development of subunit-selective proteasome substrates for Schistosoma species by MSP-MS
Description	Development of optimized subunit-specific substrates for S. mansoni proteasome (Sm20S) based on data generated by Multiplex Substrate Profiling by Mass Spectrometry (MSP-MS). MSP-MS was performed with a library of 228 synthetic tetradecapeptides. Sm20S was incubated for 1h and 3h with Bortezomib, Carfilzomib, DMSO (vehicle control), and the absence of inhibitor or vehicle control (time 0 samples). Assays were conducted in quadruplicate by incubating Sm20S with the peptide library.
HostingRepository	MassIVE
AnnounceDate	2024-10-30
AnnouncementXML	Submission_2024-10-30_14:29:02.610.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Elany Barbosa da Silva
SpeciesList	scientific name: Schistosoma mansoni; NCBI TaxID: 6183;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-10-30 13:52:16	ID requested
⏵ 1	2024-10-30 14:29:02	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: S. mansoni, Proteasome, Substrate, Bortezomib, Carfilzomib, DatasetType:Proteomics

submitter keyword: S. mansoni, Proteasome, Substrate, Bortezomib, Carfilzomib, DatasetType:Proteomics

Contact List

Anthony ODonoghue
contact affiliation	University of California San Diego
contact email	ajodonoghue@ucsd.edu
lab head
Elany Barbosa da Silva
contact affiliation	UCSD
contact email	elbarbosadasilva@health.ucsd.edu
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v07/MSV000096255/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v07/MSV000096255/