⮝ Full datasets listing
PXD057329-1
PXD057329 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Identification of clusterin binding proteins |
| Description | The mechanisms distinguishing successful cardiac regeneration from fibrotic healing remain poorly understood. In response to myocardial infarction, adult mammals typically initiate an inflammatory cascade that culminates in fibrosis, whereas neonatal mice exhibit the unique ability to regenerate cardiomyocytes (CMs). Our study employed comparative spatiotemporal single-cell analysis and genetic tools to explore the role of Clusterin (CLU) in heart regeneration. To identify CLU’s target proteins, we conducted immunoprecipitation to enrich CLU, followed by mass spectrometry to characterize its interacting proteins. |
| HostingRepository | iProX |
| AnnounceDate | 2024-10-30 |
| AnnouncementXML | Submission_2025-12-22_17:24:38.108.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yutong Wang |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-10-29 20:49:22 | ID requested | |
| ⏵ 1 | 2025-12-22 17:24:38 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: clusterin immunoprecipitation |
Contact List
| An Zeng | |
|---|---|
| contact affiliation | Center for Excellence in Molecular Cell Science |
| contact email | azeng@sibcb.ac.cn |
| lab head | |
| Yutong Wang | |
| contact affiliation | Center for Excellence in Molecular Cell Science |
| contact email | wangyutong2021@sibcb.ac.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
